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Decarboxylative hydrazination of unactivated carboxylic acids by cerium photocatalysis.

ABSTRACT: We report the cerium photocatalyzed radical decarboxylative hydrazination of carboxylic acids with di-tert-butylazodicarboxylate (DBAD). The operationally simple protocol provides rapid access to synthetically useful hydrazine derivatives and overcomes current scope limitations in the photoredox-catalyzed decarboxylation of carboxylic acids.

SUBMITTER: Yatham VR

PROVIDER: S-EPMC6498423 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature

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Decarboxylative hydrazination of unactivated carboxylic acids by cerium photocatalysis.

Yatham Veera Reddy VR Bellotti Peter P König Burkhard B

Chemical communications (Cambridge, England) 20190301 24

We report the cerium photocatalyzed radical decarboxylative hydrazination of carboxylic acids with di-tert-butylazodicarboxylate (DBAD). The operationally simple protocol provides rapid access to synthetically useful hydrazine derivatives and overcomes current scope limitations in the photoredox-catalyzed decarboxylation of carboxylic acids. ...[more]

PMID: 30829348

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