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CANDI: an R package and Shiny app for annotating radiographs and evaluating computer-aided diagnosis.


ABSTRACT:

Motivation

Radiologists have used algorithms for Computer-Aided Diagnosis (CAD) for decades. These algorithms use machine learning with engineered features, and there have been mixed findings on whether they improve radiologists' interpretations. Deep learning offers superior performance but requires more training data and has not been evaluated in joint algorithm-radiologist decision systems.

Results

We developed the Computer-Aided Note and Diagnosis Interface (CANDI) for collaboratively annotating radiographs and evaluating how algorithms alter human interpretation. The annotation app collects classification, segmentation, and image captioning training data, and the evaluation app randomizes the availability of CAD tools to facilitate clinical trials on radiologist enhancement.

Availability and implementation

Demonstrations and source code are hosted at (https://candi.nextgenhealthcare.org), and (https://github.com/mbadge/candi), respectively, under GPL-3 license.

Supplementary information

Supplementary material is available at Bioinformatics online.

SUBMITTER: Badgeley MA 

PROVIDER: S-EPMC6499410 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature

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Publications

CANDI: an R package and Shiny app for annotating radiographs and evaluating computer-aided diagnosis.

Badgeley Marcus A MA   Liu Manway M   Glicksberg Benjamin S BS   Shervey Mark M   Zech John J   Shameer Khader K   Lehar Joseph J   Oermann Eric K EK   McConnell Michael V MV   Snyder Thomas M TM   Dudley Joel T JT  

Bioinformatics (Oxford, England) 20190501 9


<h4>Motivation</h4>Radiologists have used algorithms for Computer-Aided Diagnosis (CAD) for decades. These algorithms use machine learning with engineered features, and there have been mixed findings on whether they improve radiologists' interpretations. Deep learning offers superior performance but requires more training data and has not been evaluated in joint algorithm-radiologist decision systems.<h4>Results</h4>We developed the Computer-Aided Note and Diagnosis Interface (CANDI) for collabo  ...[more]

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