Ontology highlight
ABSTRACT:
SUBMITTER: Castellanos-Rizaldos E
PROVIDER: S-EPMC6499599 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Castellanos-Rizaldos Elena E Zhang Xuan X Tadigotla Vasisht R VR Grimm Dominik G DG Karlovich Chris C Raez Luis E LE Skog Johan K JK
Oncotarget 20190423 30
Non-small cell lung cancer (NSCLC) is the most prevalent form of lung cancer and its molecular landscape has been extensively studied. The most common genetic alterations in NSCLC are mutations within the epidermal growth factor receptor (<i>EGFR</i>) gene, with frequencies between 10-40%. There are several molecular targeted therapies for patients harboring these mutations. Liquid biopsies constitute a flexible approach to monitor these mutations in real time as opposed to tissue biopsies that ...[more]