Dataset Information
Number of blood pressure measurements needed to estimate long-term visit-to-visit systolic blood pressure variability for predicting cardiovascular risk: a 10-year retrospective cohort study in a primary care clinic in Malaysia.
Ontology highlight
ABSTRACT: Objective
To determine the reproducibility of visit-to-visit blood pressure variability (BPV) in clinical practice. We also determined the minimum number of blood pressure (BP) measurements needed to estimate long-term visit-to-visit BPV for predicting 10-year cardiovascular (CV) risk.Design
Retrospective study SETTING: A primary care clinic in a university hospital in Malaysia.Participants
Random sampling of 1403 patients aged 30 years and above without any CV event at baseline.Outcomes measures
The effect of the number of BP measurement for calculation of long-term visit-to-visit BPV in predicting 10-year CV risk. CV events were defined as fatal and non-fatal coronary heart disease, fatal and non-fatal stroke, heart failure and peripheral vascular disease.Results
The mean 10-year SD of systolic blood pressure (SBP) for this cohort was 13.8±3.5?mm Hg. The intraclass correlation coefficient (ICC) for the SD of SBP based on the first eight and second eight measurements was 0.38 (p<0.001). In a primary care setting, visit-to-visit BPV (SD of SBP calculated from 20?BP measurements) was significantly associated with CV events (adjusted OR 1.07, 95%?CI 1.02 to 1.13, p=0.009). Using SD of SBP from 20 measurement as reference, SD of SBP from 6 measurements (median time 1.75 years) has high reliability (ICC 0.74, p<0.001), with a mean difference of 0.6?mm Hg. Hence, a minimum of six BP measurements is needed for reliably estimating intraindividual BPV for CV outcome prediction.Conclusion
Long-term visit-to-visit BPV is reproducible in clinical practice. We suggest a minimum of six?BP measurements for calculation of intraindividual visit-to-visit BPV. The number and duration of BP readings to derive BPV should be taken into consideration in predicting long-term CV risk.
SUBMITTER: Lim HM
PROVIDER: S-EPMC6500269 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Publications
Number of blood pressure measurements needed to estimate long-term visit-to-visit systolic blood pressure variability for predicting cardiovascular risk: a 10-year retrospective cohort study in a primary care clinic in Malaysia.
BMJ open 20190420 4
<h4>Objective</h4>To determine the reproducibility of visit-to-visit blood pressure variability (BPV) in clinical practice. We also determined the minimum number of blood pressure (BP) measurements needed to estimate long-term visit-to-visit BPV for predicting 10-year cardiovascular (CV) risk.<h4>Design</h4>Retrospective study SETTING: A primary care clinic in a university hospital in Malaysia.<h4>Participants</h4>Random sampling of 1403 patients aged 30 years and above without any CV event at b ...[more]