Safety of Dynamic Intravenous Iron Administration Strategies in Hemodialysis Patients.

ABSTRACT:

Background and objectives

Intravenous iron therapy for chronic anemia management is largely driven by dosing protocols that differ in intensity with respect to dosing approach (i.e., dose, frequency, and duration). Little is known about the safety of these protocols.

Design, setting, participants, & measurements

Using clinical data from a large United States dialysis provider linked to health care utilization data from Medicare, we constructed a cohort of patients with ESKD aged ≥65 years who initiated and continued center-based hemodialysis for ≥90 days between 2009 and 2012, and initiated at least one of the five common intravenous iron administration strategies; ranked by intensity (the amount of iron given at moderate-to-high iron indices), the order of strategies

SUBMITTER: Li X 

PROVIDER: S-EPMC6500950 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature