Ontology highlight
ABSTRACT:
SUBMITTER: Farafonov VS
PROVIDER: S-EPMC6501343 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Farafonov Vladimir S VS Nerukh Dmitry D
Interface focus 20190419 3
The all-atom model of an MS2 bacteriophage particle without its genome (the capsid) was built using high-resolution cryo-electron microscopy (EM) measurements for initial conformation. The structural characteristics of the capsid and the dynamics of the surrounding solution were examined using molecular dynamics simulation. The model demonstrates the overall preservation of the cryo-EM structure of the capsid at physiological conditions (room temperature and ions composition). The formation of a ...[more]