Ontology highlight
ABSTRACT:
SUBMITTER: Kanazawa M
PROVIDER: S-EPMC6501515 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Kanazawa Masato M Takahashi Tetsuya T Ishikawa Masanori M Onodera Osamu O Shimohata Takayoshi T Del Zoppo Gregory J GJ
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20190306 5
The ischemic penumbra is both a concept in understanding the evolution of cerebral tissue injury outcome of focal ischemia and a potential therapeutic target for ischemic stroke. In this review, we examine the evidence that angiogenesis can contribute to beneficial outcomes following focal ischemia in model systems. Several studies have shown that, following cerebral ischemia, endothelial proliferation and subsequent angiogenesis can be detected beginning four days after cerebral ischemia in the ...[more]