Gestational route to healthy birth (GaRBH): protocol for an Indian prospective cohort study.

ABSTRACT:

Introduction

Pregnancy is characterised by a high rate of metabolic shifts from early to late phases of gestation in order to meet the raised physiological and metabolic needs. This change in levels of metabolites is influenced by gestational weight gain (GWG), which is an important characteristic of healthy pregnancy. Inadequate/excessive GWG has short-term and long-term implications on maternal and child health. Exploration of gestational metabolism is required for understanding the quantitative changes in metabolite levels during the course of pregnancy. Therefore, our aim is to study trimester-specific variation in levels of metabolites in relation to GWG and its influence on fetal growth and newborn anthropometric traits at birth.

Methods and analysis

A prospective long

SUBMITTER: Gupta V 

PROVIDER: S-EPMC6501957 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature