Ontology highlight
ABSTRACT:
SUBMITTER: Garcia-Fernandez S
PROVIDER: S-EPMC6502822 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
García-Fernández Sergio S Frentrup Martinique M Steglich Matthias M Gonzaga Aitor A Cobo Marta M López-Fresneña Nieves N Cobo Javier J Morosini María-Isabel MI Cantón Rafael R Del Campo Rosa R Nübel Ulrich U
Scientific reports 20190506 1
To trace the routes and frequencies of transmission of Clostridioides difficile in a tertiary-care hospital in Madrid (Spain), we sequenced the genomes from all C. difficile isolates collected over 36 months (2014-2016) that were indistinguishable from any other isolate by PCR ribotyping. From a total of 589 C. difficile infection cases, we cultivated and PCR-ribotyped 367 C. difficile isolates (62%), of which 265 were genome-sequenced. Based on close relatedness of successively collected isolat ...[more]