The dynamic relationships between the active and catabolic vitamin D metabolites, their ratios, and associations with PTH.
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ABSTRACT:
SUBMITTER: Tang JCY
PROVIDER: S-EPMC6502854 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
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The dynamic relationships between the active and catabolic vitamin D metabolites, their ratios, and associations with PTH.
Tang Jonathan C Y JCY Jackson Sarah S Walsh Neil P NP Greeves Julie J Fraser William D WD
Scientific reports 20190506 1
Vitamin D status, assessed by serum concentration of 25(OH)D, is the prime candidate marker for many disease-association studies, but the interplay between the subsequent 1,25-dihydroxyvitamin D (1,25(OH)<sub>2</sub>D) and 24,25-dihydroxyvitamin D (24,25(OH)<sub>2</sub>D) metabolites is unclear. In this study, we conducted an analysis from a large cohort of healthy, physically fit, young army recruits (n = 940). We found a significant, inverse relationship between serum 25(OH)D and 1,25(OH)<sub> ...[more]
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