Ontology highlight
ABSTRACT:
SUBMITTER: de Wijn R
PROVIDER: S-EPMC6503916 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
IUCrJ 20190419 Pt 3
Determining optimal conditions for the production of well diffracting crystals is a key step in every biocrystallography project. Here, a microfluidic device is described that enables the production of crystals by counter-diffusion and their direct on-chip analysis by serial crystallography at room temperature. Nine 'non-model' and diverse biomacromolecules, including seven soluble proteins, a membrane protein and an RNA duplex, were crystallized and treated on-chip with a variety of standard te ...[more]