Ontology highlight
ABSTRACT:
SUBMITTER: Holloway EM
PROVIDER: S-EPMC6503984 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Development (Cambridge, England) 20190416 8
Organoids are complex three-dimensional <i>in vitro</i> organ-like model systems. Human organoids, which are derived from human pluripotent stem cells or primary human donor tissue, have been used to address fundamental questions about human development, stem cell biology and organ regeneration. Focus has now shifted towards implementation of organoids for biological discovery and advancing existing systems to more faithfully recapitulate the native organ. This work has highlighted significant u ...[more]