Ontology highlight
ABSTRACT:
SUBMITTER: Qian X
PROVIDER: S-EPMC6503989 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Qian Xuyu X Song Hongjun H Ming Guo-Li GL
Development (Cambridge, England) 20190416 8
Brain organoids are self-assembled three-dimensional aggregates generated from pluripotent stem cells with cell types and cytoarchitectures that resemble the embryonic human brain. As such, they have emerged as novel model systems that can be used to investigate human brain development and disorders. Although brain organoids mimic many key features of early human brain development at molecular, cellular, structural and functional levels, some aspects of brain development, such as the formation o ...[more]