Ontology highlight
ABSTRACT:
SUBMITTER: Hong S
PROVIDER: S-EPMC6504211 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Hong Seunghee S Banchereau Romain R Maslow Bat-Sheva L BL Guerra Marta M MM Cardenas Jacob J Baisch Jeanine J Branch D Ware DW Porter T Flint TF Sawitzke Allen A Laskin Carl A CA Buyon Jill P JP Merrill Joan J Sammaritano Lisa R LR Petri Michelle M Gatewood Elizabeth E Cepika Alma-Martina AM Ohouo Marina M Obermoser Gerlinde G Anguiano Esperanza E Kim Tae Whan TW Nulsen John J Nehar-Belaid Djamel D Blankenship Derek D Turner Jacob J Banchereau Jacques J Salmon Jane E JE Pascual Virginia V
The Journal of experimental medicine 20190408 5
Systemic lupus erythematosus carries an increased risk of pregnancy complications, including preeclampsia and fetal adverse outcomes. To identify the underlying molecular mechanisms, we longitudinally profiled the blood transcriptome of 92 lupus patients and 43 healthy women during pregnancy and postpartum and performed multicolor flow cytometry in a subset of them. We also profiled 25 healthy women undergoing assisted reproductive technology to monitor transcriptional changes around embryo impl ...[more]