Ontology highlight
ABSTRACT:
SUBMITTER: Guenthart BA
PROVIDER: S-EPMC6504972 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Guenthart Brandon A BA O'Neill John D JD Kim Jinho J Queen Dawn D Chicotka Scott S Fung Kenmond K Simpson Michael M Donocoff Rachel R Salna Michael M Marboe Charles C CC Cunningham Katherine K Halligan Susan P SP Wobma Holly M HM Hozain Ahmed E AE Romanov Alexander A Vunjak-Novakovic Gordana G Bacchetta Matthew M
Nature communications 20190507 1
The number of available donor organs limits lung transplantation, the only lifesaving therapy for the increasing population of patients with end-stage lung disease. A prevalent etiology of injury that renders lungs unacceptable for transplantation is gastric aspiration, a deleterious insult to the pulmonary epithelium. Currently, severely damaged donor lungs cannot be salvaged with existing devices or methods. Here we report the regeneration of severely damaged lungs repaired to meet transplanta ...[more]