Ferroptosis and Its Role in Diverse Brain Diseases.
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ABSTRACT:
SUBMITTER: Weiland A
PROVIDER: S-EPMC6506411 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Publications
Ferroptosis and Its Role in Diverse Brain Diseases.
Weiland Abigail A Wang Yamei Y Wu Weihua W Lan Xi X Han Xiaoning X Li Qian Q Wang Jian J
Molecular neurobiology 20181108 7
Ferroptosis is a recently identified, iron-regulated, non-apoptotic form of cell death. It is characterized by cellular accumulation of lipid reactive oxygen species that ultimately leads to oxidative stress and cell death. Although first identified in cancer cells, ferroptosis has been shown to have significant implications in several neurologic diseases, such as ischemic and hemorrhagic stroke, Alzheimer's disease, and Parkinson's disease. This review summarizes current research on ferroptosis ...[more]
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