Ontology highlight
ABSTRACT:
SUBMITTER: Martinez P
PROVIDER: S-EPMC6506443 | biostudies-literature | 2013 Dec
REPOSITORIES: biostudies-literature
Scientific reports 20131203
Despite recent progress thanks to next-generation sequencing technologies, personalised cancer medicine is still hampered by intra-tumour heterogeneity and drug resistance. As most patients with advanced metastatic disease face poor survival, there is need to improve early diagnosis. Analysing circulating tumour DNA (ctDNA) might represent a non-invasive method to detect mutations in patients, facilitating early detection. In this article, we define reduced gene panels from publicly available da ...[more]