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Fungal keratitis caused by Didymella gardeniae (formerly Phoma gardeniae) successfully treated with topical voriconazole and miconazole.


ABSTRACT: Fungal keratitis by Phoma species is rare, and little information has been accumulated. We report a case of keratitis caused by Didymella gardeniae, formerly known as P. gardeniae. The patient had a history of stromal herpetic keratitis and had been treated with long-term topical betamethasone. He developed infectious keratitis in the left eye, with the causative fungus identified by ribosomal DNA sequencing. Combination treatment with topical voriconazole and miconazole proved effective.

SUBMITTER: Miyakubo T 

PROVIDER: S-EPMC6506558 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature

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Fungal keratitis caused by <i>Didymella gardeniae</i> (formerly <i>Phoma gardeniae</i>) successfully treated with topical voriconazole and miconazole.

Miyakubo Tomoko T   Todokoro Daisuke D   Makimura Koichi K   Akiyama Hideo H  

Medical mycology case reports 20190427


Fungal keratitis by <i>Phoma</i> species is rare, and little information has been accumulated. We report a case of keratitis caused by <i>Didymella gardeniae</i>, formerly known as <i>P. gardeniae</i>. The patient had a history of stromal herpetic keratitis and had been treated with long-term topical betamethasone. He developed infectious keratitis in the left eye, with the causative fungus identified by ribosomal DNA sequencing. Combination treatment with topical voriconazole and miconazole pro  ...[more]

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