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Adrenal hemorrhage in newborn: how, when and why- from case report to literature review.

ABSTRACT:

Background

Neonatal adrenal hemorrhage is a relatively uncommon condition (0.2-0.55%). Various risk factors have been reported in addition to birth asphyxia, such as sepsis, coagulation disorders, traumatic delivery, and perinatal injuries. Adrenal hemorrhage usually affects the right adrenal gland (about 70% of cases) while it involves the bilateral adrenal gland only in 10% of cases. In most cases, the event is asymptomatic but, in others, it may be so devastating to determine death by bleeding or adrenal insufficiency.

Case presentation

A case of bilateral neonatal adrenal hemorrhage, with adrenal insufficiency, but with no important risk factors and favorable evolution in a male infant.

Conclusions

This case emphasizes the importance of keeping a non-interventional attitude, avoiding early surgery but carrying out a serial sonographic follow-up. Serial ultrasound monitoring is the most reliable approach during conservative management.

SUBMITTER: Toti MS

PROVIDER: S-EPMC6507044 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature

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Adrenal hemorrhage in newborn: how, when and why- from case report to literature review.

Toti M S MS Ghirri P P Bartoli A A Caputo C C Laudani E E Masoni F F Mele L L Bernardini R R

Italian journal of pediatrics 20190508 1

<h4>Background</h4>Neonatal adrenal hemorrhage is a relatively uncommon condition (0.2-0.55%). Various risk factors have been reported in addition to birth asphyxia, such as sepsis, coagulation disorders, traumatic delivery, and perinatal injuries. Adrenal hemorrhage usually affects the right adrenal gland (about 70% of cases) while it involves the bilateral adrenal gland only in 10% of cases. In most cases, the event is asymptomatic but, in others, it may be so devastating to determine death by ...[more]

PMID: 31068206

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