Ontology highlight
ABSTRACT:
SUBMITTER: Manheim EA
PROVIDER: S-EPMC65074 | biostudies-literature | 2002 Jan
REPOSITORIES: biostudies-literature
Manheim Elizabeth A EA Jang Janet K JK Dominic Danielle D McKim Kim S KS
Molecular biology of the cell 20020101 1
During Drosophila oogenesis, the oocyte is formed within a 16-cell cyst immediately after four incomplete cell divisions. One of the primary events in oocyte development is meiotic recombination. Here, we report the intracellular localization of the MEI-218 protein that is specifically required for meiotic crossing-over. To understand the role of mei-218 in meiosis and to study the regulation of genes required for meiotic recombination, we characterized the expression pattern of its RNA and prot ...[more]