Mindfulness-based relapse prevention for alcohol dependence: Findings from a randomized controlled trial.

ABSTRACT: OBJECTIVES:To assess the effects of mindfulness-based relapse prevention for alcohol dependence (MBRP-A) intervention on drinking and related consequences. METHODS:123 alcohol-dependent adults in early recovery, recruited from outpatient treatment programs, were randomly assigned to MBRP-A (intervention plus usual-care; N?=?64) or Control (usual-care-alone; N?=?59) group. MBRP-A consisted of eight-weekly sessions and home practice. Outcomes were assessed at baseline, 8?weeks and 26?weeks (18?weeks post-intervention), and compared between groups using repeated measures analysis. RESULTS:Outcome analysis included 112 participants (57 MBRP-A; 55 Control) who provided follow-up data. Participants were 41.0?±?12.2?years old, 56.2% male, and 91% white. Prior to "quit date," they reported drinking on 59.4?±?34.8% (averaging 6.1?±?5.0 drinks/day) and heavy drinking (HD) on 50.4?±?35.5% of days. Their drinking reduced after the "quit date" (before enrollment) to 0.4?±?1.7% (HD: 0.1?±?0.7%) of days. At 26?weeks, the MBRP-A and control groups reported any drinking on 11.5?±?22.5% and 5.9?±?11.6% of days and HD on 4.5?±?9.3% and 3.2?±?8.7% of days, respectively, without between-group differences (ps???0.05) in drinking or related consequences during the follow-up period. Three MBRP-A participants reported "relapse," defined as three-consecutive HD days, during the study. Subgroup analysis indicated that greater adherence to session attendance and weekly home practice minutes were associated with improved outcomes. CONCLUSIONS:MBRP-A as an adjunct to usual-care did not show to improve outcomes in alcohol-dependent adults in early recovery compared to usual-care-alone; a return to drinking and relapse to HD were rare in both groups. However, greater adherence to MBRP-A intervention may improve long-term drinking-related outcomes.

SUBMITTER: Zgierska AE 

PROVIDER: S-EPMC6508889 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature