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Binodal, wireless epidermal electronic systems with in-sensor analytics for neonatal intensive care.


ABSTRACT: Existing vital sign monitoring systems in the neonatal intensive care unit (NICU) require multiple wires connected to rigid sensors with strongly adherent interfaces to the skin. We introduce a pair of ultrathin, soft, skin-like electronic devices whose coordinated, wireless operation reproduces the functionality of these traditional technologies but bypasses their intrinsic limitations. The enabling advances in engineering science include designs that support wireless, battery-free operation; real-time, in-sensor data analytics; time-synchronized, continuous data streaming; soft mechanics and gentle adhesive interfaces to the skin; and compatibility with visual inspection and with medical imaging techniques used in the NICU. Preliminary studies on neonates admitted to operating NICUs demonstrate performance comparable to the most advanced clinical-standard monitoring systems.

SUBMITTER: Chung HU 

PROVIDER: S-EPMC6510306 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature

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Binodal, wireless epidermal electronic systems with in-sensor analytics for neonatal intensive care.

Chung Ha Uk HU   Kim Bong Hoon BH   Lee Jong Yoon JY   Lee Jungyup J   Xie Zhaoqian Z   Ibler Erin M EM   Lee KunHyuck K   Banks Anthony A   Jeong Ji Yoon JY   Kim Jongwon J   Ogle Christopher C   Grande Dominic D   Yu Yongjoon Y   Jang Hokyung H   Assem Pourya P   Ryu Dennis D   Kwak Jean Won JW   Namkoong Myeong M   Park Jun Bin JB   Lee Yechan Y   Kim Do Hoon DH   Ryu Arin A   Jeong Jaeseok J   You Kevin K   Ji Bowen B   Liu Zhuangjian Z   Huo Qingze Q   Feng Xue X   Deng Yujun Y   Xu Yeshou Y   Jang Kyung-In KI   Kim Jeonghyun J   Zhang Yihui Y   Ghaffari Roozbeh R   Rand Casey M CM   Schau Molly M   Hamvas Aaron A   Weese-Mayer Debra E DE   Huang Yonggang Y   Lee Seung Min SM   Lee Chi Hwan CH   Shanbhag Naresh R NR   Paller Amy S AS   Xu Shuai S   Rogers John A JA  

Science (New York, N.Y.) 20190301 6430


Existing vital sign monitoring systems in the neonatal intensive care unit (NICU) require multiple wires connected to rigid sensors with strongly adherent interfaces to the skin. We introduce a pair of ultrathin, soft, skin-like electronic devices whose coordinated, wireless operation reproduces the functionality of these traditional technologies but bypasses their intrinsic limitations. The enabling advances in engineering science include designs that support wireless, battery-free operation; r  ...[more]

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