Ontology highlight
ABSTRACT:
SUBMITTER: Gujral S
PROVIDER: S-EPMC6511318 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Gujral Swathi S Aizenstein Howard H Reynolds Charles F CF Butters Meryl A MA Grove George G Karp Jordan F JF Erickson Kirk I KI
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 20190117 6
<h4>Objective</h4>The aim of this study was to test the feasibility of an exercise augmentation to pharmacotherapy in depressed younger and older adults while exploring neural mechanisms.<h4>Methods</h4>A randomized, double-blind, controlled clinical trial was conducted in 15 inactive younger (20-39 years) and older (60-79 years) adults meeting Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, criteria for a major depressive episode (https://clinicaltrials.gov/ct2/show/NCT024 ...[more]