Ontology highlight
ABSTRACT:
SUBMITTER: Franke M
PROVIDER: S-EPMC6511743 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Franke Maximilian M Conzelmann Annette A Grünblatt Edna E Werling Anna M AM Spieles Helen H Wewetzer Christoph C Warnke Andreas A Romanos Marcel M Walitza Susanne S Renner Tobias J TJ
Frontiers in molecular neuroscience 20190503
Obsessive-compulsive disorder (OCD) causes severe distress and is therefore counted by the World Health Organisation (WHO) as one of the 10 most impairing illnesses. There is evidence for a strong genetic underpinning especially in early onset OCD (eoOCD). Though several genes involved in neurotransmission have been reported as candidates, there is still a need to identify new pathways. In this study, we focussed on genetic variants of the Neuropeptide Y (NPY) system. NPY is one of the most abun ...[more]