Ontology highlight
ABSTRACT:
SUBMITTER: Lee C
PROVIDER: S-EPMC6512917 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Molecular & cellular oncology 20190215 2
Cellular stress response is coordinated through the communication between mitochondria and the nucleus. However, whereas mitochondria are regulated by nuclear-encoded proteins, the nucleus was considered ungoverned by mitochondrial-encoded factors. We recently reported that a mitochondrial-encoded peptide directly regulates the nuclear genome upon cellular stress, indicating an integrated bi-genomic cross-communication mechanism. ...[more]