Ontology highlight
ABSTRACT:
SUBMITTER: Butler WN
PROVIDER: S-EPMC6516752 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Butler William N WN Hardcastle Kiah K Giocomo Lisa M LM
Science (New York, N.Y.) 20190301 6434
Ethologically relevant navigational strategies often incorporate remembered reward locations. Although neurons in the medial entorhinal cortex provide a maplike representation of the external spatial world, whether this map integrates information regarding learned reward locations remains unknown. We compared entorhinal coding in rats during a free-foraging task and a spatial memory task. Entorhinal spatial maps restructured to incorporate a learned reward location, which in turn improved positi ...[more]