Methodological factors influencing inhalation bioaccessibility of metal(loid)s in PM2.5 using simulated lung fluid.
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ABSTRACT:
SUBMITTER: Kastury F
PROVIDER: S-EPMC6517839 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
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Methodological factors influencing inhalation bioaccessibility of metal(loid)s in PM<sub>2.5</sub> using simulated lung fluid.
Kastury Farzana F Smith E E Karna Ranju R RR Scheckel Kirk G KG Juhasz A L AL
Environmental pollution (Barking, Essex : 1987) 20180607
In this study, methodological factors influencing the dissolution of metal(loid)s in simulated lung fluid (SLF) was assessed in order to develop a standardised method for the assessment of inhalation bioaccessibility in PM<sub>2.5</sub>. To achieve this aim, the effects of solid to liquid (S/L) ratio (1:100 to 1:5000), agitation (magnetic agitation, occasional shaking, orbital and end-over-end rotation), composition of SLF (artificial lysosomal fluid: ALF; phagolysosomal simulant fluid: PSF) and ...[more]
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