Estimating seasonal variation in Australian pertussis notifications from 1991 to 2016: evidence of spring to summer peaks.

ABSTRACT: Unlike for many other respiratory infections, the seasonality of pertussis is not well understood. While evidence of seasonal fluctuations in pertussis incidence has been noted in some countries, there have been conflicting findings including in the context of Australia. We investigated this issue by analysing the seasonality of pertussis notifications in Australia using monthly data from January 1991 to December 2016. Data were made available for all states and territories in Australia except for the Australian Capital Territory and were stratified into age groups. Using a time-series decomposition approach, we formulated a generalised additive model where seasonality is expressed using cosinor terms to estimate the amplitude and peak timing of pertussis notifications in Australia. We als

SUBMITTER: Leong RNF 

PROVIDER: S-EPMC6518527 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature