Ontology highlight
ABSTRACT:
SUBMITTER: Vaz Fragoso CA
PROVIDER: S-EPMC6519718 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Respiratory medicine 20190329
<h4>Background</h4>Clinical trials of COPD pharmacotherapy typically involve aging populations with moderate-to-severe COPD, but the latter is often diagnosed by spirometric criteria that are not age-appropriate across the continuum of lung function. We have therefore re-evaluated the clinical effect of combination therapy (salmeterol plus fluticasone) in moderate-to-severe COPD, using more age-appropriate spirometric criteria from the Global Lung Function Initiative (GLI) and trial data from To ...[more]