Ontology highlight
ABSTRACT:
SUBMITTER: Lu S
PROVIDER: S-EPMC6519901 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Lu Shun S Catalano Calogerina C Huhn Stefanie S Pardini Barbara B Partu Linda L Vymetalkova Veronika V Vodickova Ludmila L Levy Miroslav M Buchler Thomas T Hemminki Kari K Vodicka Pavel P Försti Asta A
PloS one 20190515 5
Mucins and their glycosylation have been suggested to play an important role in colorectal carcinogenesis. We examined potentially functional genetic variants in the mucin genes or genes involved in their glycosylation with respect to colorectal cancer (CRC) risk and clinical outcome. We genotyped 23 single nucleotide polymorphisms (SNPs) covering 123 SNPs through pairwise linkage disequilibrium (r2>0.80) in the MUC1, MUC2, MUC4, MUC5AC, MUC6, and B3GNT6 genes in a hospital-based case-control st ...[more]