Ontology highlight
ABSTRACT:
SUBMITTER: Cornely OA
PROVIDER: S-EPMC6520315 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Cornely Oliver A OA Vehreschild Maria J G T MJGT Adomakoh Nicholas N Georgopali Areti A Karas Andreas A Kazeem Gbenga G Guery Benoit B
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20190325 6
Poor outcomes following Clostridium difficile infection (CDI) have been associated with advanced age, presence of cancer and C. difficile PCR-ribotype 027. The impact of baseline risk factors on clinical outcomes was evaluated using data from the EXTEND study, in which rate of sustained clinical cure (SCC) in the overall population was significantly higher with an extended-pulsed fidaxomicin (EPFX) regimen than with vancomycin. Patients aged ≥ 60 years received EPFX (fidaxomicin 200 mg twice dai ...[more]