Ontology highlight
ABSTRACT:
SUBMITTER: Jiang Y
PROVIDER: S-EPMC6521168 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Jiang Yixin Y Spurny Manuela M Schübel Ruth R Nonnenmacher Tobias T Schlett Christopher L CL von Stackelberg Oyunbileg O Ulrich Cornelia M CM Kaaks Rudolf R Kauczor Hans-Ulrich HU Kühn Tilman T Nattenmüller Johanna J
Nutrients 20190423 4
<h4>Background</h4>Obesity can lead to ectopic pancreatic fat accumulation and increase the risk for type 2 diabetes. Smaller intervention trials have shown a decrease in pancreatic fat content (PFC) with weight loss, and we intended to investigate the effects of weight loss on PFC in a larger trial.<h4>Methods</h4>Data from the HELENA-Trial, a randomized controlled trial (RCT) among 137 non-diabetic obese adults were used. The study cohort was classified into 4 quartiles based on weight change ...[more]