Ontology highlight
ABSTRACT:
SUBMITTER: Cernigliaro C
PROVIDER: S-EPMC6521343 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Cernigliaro Cesare C D'Anneo Antonella A Carlisi Daniela D Giuliano Michela M Marino Gammazza Antonella A Barone Rosario R Barone Rosario R Longhitano Lucia L Cappello Francesco F Emanuele Sonia S Distefano Alfio A Campanella Claudia C Calvaruso Giuseppe G Lauricella Marianna M
Cancers 20190410 4
Epidemiological studies suggest that chronic alcohol consumption is a lifestyle risk factor strongly associated with colorectal cancer development and progression. The aim of the present study was to examine the effect of ethanol (EtOH) on survival and progression of three different colon cancer cell lines (HCT116, HT29, and Caco-2). Our data showed that EtOH induces oxidative and endoplasmic reticulum (ER) stress, as demonstrated by reactive oxygen species (ROS) and ER stress markers Grp78, ATF ...[more]