Ontology highlight
ABSTRACT:
SUBMITTER: Zacher J
PROVIDER: S-EPMC6524751 | biostudies-literature | 2014 Jun
REPOSITORIES: biostudies-literature
Zacher Jonas J Kasenda Benjamin B Engert Andreas A Skoetz Nicole N
The Cochrane database of systematic reviews 20140616 6
<h4>Background</h4>Prior to the introduction of the chemotherapeutic agent methotrexate, radiotherapy was the sole, first-line option for the treatment of individuals with primary central nervous system lymphoma (PCNSL), Now that methotrexate is available, the role of radiotherapy in the treatment of PCNSL has been called into question. Although various studies suggest promising results with regard to overall and progression-free survival with the use of chemotherapeutic regimens alone as well a ...[more]