Ontology highlight
ABSTRACT:
SUBMITTER: Da Costa AS
PROVIDER: S-EPMC6525503 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Proceedings of the National Academy of Sciences of the United States of America 20190429 20
Immunological memory exists so that following infection an expanded population of pathogen-specific lymphocytes can rapidly and efficiently control infection in the case of reexposure. However, in the case of CD8+ T lymphocytes, a population of unconventional CD44+CD122+ virtual memory T cells (T<sub>VM</sub>) has been described that possesses many, though not all, features of "true memory" T cells, without the requirement of first encountering cognate antigen. Here, we demonstrate a role for re ...[more]