Identification of Macrophage Genotype and Key Biological Pathways in Circulating Angiogenic Cell Transcriptome.
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ABSTRACT:
SUBMITTER: Everaert BR
PROVIDER: S-EPMC6525806 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
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Identification of Macrophage Genotype and Key Biological Pathways in Circulating Angiogenic Cell Transcriptome.
Everaert Bert R BR Van Laere Steven J SJ Lembrechts Robrecht R Hoymans Vicky Y VY Timmermans Jean-Pierre JP Vrints Christiaan J CJ
Stem cells international 20190502
<h4>Background</h4>Circulating angiogenic cells (CAC) have been identified as important regulators of vascular biology. However, there is still considerable debate about the genotype and function of CAC.<h4>Methods and results</h4>Data from publicly available gene expression data sets were used to analyse the transcriptome of in vitro cultured CAC (CAC<sub>iv</sub>). Genes and pathways of interest were further evaluated using qPCR comparing CAC<sub>iv</sub> versus CD14<sup>+</sup> monocytic cell ...[more]
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