Ontology highlight
ABSTRACT:
SUBMITTER: Gasior K
PROVIDER: S-EPMC6527395 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
Cell adhesion & migration 20181008 1
The epithelial mesenchymal transition (EMT) is one step in the process through which carcinoma cells metastasize by gaining the cellular mobility associated with mesenchymal cells. This work examines the dual influence of the TGF-β pathway and intercellular contact on the activation of EMT in colon (SW480) and breast (MCF7) carcinoma cells. While the SW480 population revealed an intermediate state between the epithelial and mesenchymal states, the MC7 cells exhibited highly adhesive behavior. Ho ...[more]