Ontology highlight
ABSTRACT:
SUBMITTER: Spencer TM
PROVIDER: S-EPMC6527425 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Spencer Teresa M TM Blumenstein Ryan F RF Pryse Kenneth M KM Lee Sheng-Lin SL Glaubke David A DA Carlson Brian E BE Elson Elliot L EL Genin Guy M GM
ACS biomaterials science & engineering 20161018 11
Myocardial function deteriorates over the course of fibrotic cardiomyopathy, due to electrophysiological and mechanical effects of myofibroblasts that are not completely understood. Although a range of experimental model systems and associated theoretical treatments exist at the levels of isolated cardiomyocytes and planar co-cultures of myofibroblasts and cardiomyocytes, interactions between these cell types at the tissue level are less clear. We studied these interactions through an engineered ...[more]