Dataset Information

Proteomic and Metabolomic Characteristics of Extremophilic Fungi Under Simulated Mars Conditions.

ABSTRACT: Filamentous fungi have been associated with extreme habitats, including nuclear power plant accident sites and the International Space Station (ISS). Due to their immense adaptation and phenotypic plasticity capacities, fungi may thrive in what seems like uninhabitable niches. This study is the first report of fungal survival after exposure of monolayers of conidia to simulated Mars conditions (SMC). Conidia of several Chernobyl nuclear accident-associated and ISS-isolated strains were tested for UV-C and SMC sensitivity, which resulted in strain-dependent survival. Strains surviving exposure to SMC for 30 min, ISSFT-021-30 and IMV 00236-30, were further characterized for proteomic, and metabolomic changes. Differential expression of proteins involved in ribosome biogenesis, translation, and carbohydrate metabolic processes was observed. No significant metabolome alterations were revealed. Lastly, ISSFT-021-30 conidia re-exposed to UV-C exhibited enhanced UV-C resistance when compared to the conidia of unexposed ISSFT-021.

SUBMITTER: Blachowicz A

PROVIDER: S-EPMC6529585 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature

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Proteomic and Metabolomic Characteristics of Extremophilic Fungi Under Simulated Mars Conditions.

Blachowicz Adriana A Chiang Abby J AJ Elsaesser Andreas A Kalkum Markus M Ehrenfreund Pascale P Stajich Jason E JE Torok Tamas T Wang Clay C C CCC Venkateswaran Kasthuri K

Frontiers in microbiology 20190515

Filamentous fungi have been associated with extreme habitats, including nuclear power plant accident sites and the International Space Station (ISS). Due to their immense adaptation and phenotypic plasticity capacities, fungi may thrive in what seems like uninhabitable niches. This study is the first report of fungal survival after exposure of monolayers of conidia to simulated Mars conditions (SMC). Conidia of several Chernobyl nuclear accident-associated and ISS-isolated strains were tested fo ...[more]

PMID: 31156574

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Dataset Information

Proteomic and Metabolomic Characteristics of Extremophilic Fungi Under Simulated Mars Conditions.

Publications

Proteomic and Metabolomic Characteristics of Extremophilic Fungi Under Simulated Mars Conditions.

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