Dataset Information

Psychotropic drug use following venous thromboembolism versus diabetes mellitus in adolescence or young adulthood: a Danish nationwide cohort study.

ABSTRACT:

Objectives

Critical and chronic illness in youth such as diabetes can lead to impaired mental health. Despite the potentially traumatic and life-threatening nature of venous thromboembolism (VTE), the long-term mental health of adolescents and young adults with VTE is unclear. We compared the long-term mental health of adolescents and young adults with VTE versus adolescents and young adults with insulin-dependent diabetes mellitus (IDDM) using psychotropic drug purchase as proxy for mental health.

Design

Nationwide registry-based cohort study.

Setting

Denmark 1997-2015.

Participants

All patients aged 13-33 years with an incident diagnosis of VTE (n=5065) or IDDM (n=6609).

Exposure

First time primary hospital diagnosis of VTE or IDDM.

Primary and secondary outcome measures

Adjusted absolute risk and risk difference at 1 and 5 years follow-up for first psychotropic drug purchase comparing patients with VTE and patients with IDDM.

Results

The absolute 1?year risk of psychotropic drug use was 6.2% among VTE patients versus 3.6% among patients with IDDM, at 5 years this was 19.3%-14.7%, respectively. After adjusting for the effect of sex, age and risk factors for VTE this corresponded to a 1?year risk differences of 1.9% (95 % CI 0.1% to 3.3%). At 5?years follow-up the risk difference was 1.9% (95% CI 0.5% to 3.3%).

Conclusion

One-fifth of adolescents and young adults with incident VTE had claimed a prescription for a psychotropic drug within 5 years, a risk comparable to that of young patients with IDDM.

SUBMITTER: Hojen AA

PROVIDER: S-EPMC6530366 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature

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Publications

Psychotropic drug use following venous thromboembolism versus diabetes mellitus in adolescence or young adulthood: a Danish nationwide cohort study.

Højen Anette Arbjerg AA Søgaard Mette M Melgaard Line L Lane Deirdre A DA Sørensen Erik Elgaard EE Goldhaber Samuel Zachary SZ Larsen Torben Bjerregaard TB

BMJ open 20190514 5

<h4>Objectives</h4>Critical and chronic illness in youth such as diabetes can lead to impaired mental health. Despite the potentially traumatic and life-threatening nature of venous thromboembolism (VTE), the long-term mental health of adolescents and young adults with VTE is unclear. We compared the long-term mental health of adolescents and young adults with VTE versus adolescents and young adults with insulin-dependent diabetes mellitus (IDDM) using psychotropic drug purchase as proxy for men ...[more]

PMID: 31092651

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Dataset Information

Psychotropic drug use following venous thromboembolism versus diabetes mellitus in adolescence or young adulthood: a Danish nationwide cohort study.

Objectives

Design

Setting

Participants

Exposure

Primary and secondary outcome measures

Results

Conclusion

Publications

Psychotropic drug use following venous thromboembolism versus diabetes mellitus in adolescence or young adulthood: a Danish nationwide cohort study.

Similar Datasets

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