Ontology highlight
ABSTRACT:
SUBMITTER: Laine JE
PROVIDER: S-EPMC6531675 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Laine Jessica E JE Ilievski Vesna V Richardson David B DB Herring Amy H AH Stýblo Miroslav M Rubio-Andrade Marisela M Garcia-Vargas Gonzalo G Gamble Mary V MV Fry Rebecca C RC
Journal of exposure science & environmental epidemiology 20180801 5
The prenatal period represents a critical window of susceptibility to inorganic arsenic (iAs) exposure from contaminated drinking water. Ingested iAs undergoes hepatic methylation generating mono and di-methyl arsenicals (MMAs and DMAs, respectively), a process that facilitates urinary arsenic (As) elimination. Differences in pregnant women's metabolism of As as indicated by greater proportions of MMAs and smaller proportions of DMAs in urine are a risk factor for adverse birth outcomes. One ca ...[more]