Ontology highlight
ABSTRACT:
SUBMITTER: Kobayashi T
PROVIDER: S-EPMC6532063 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Kobayashi Tetsuro T Voisin Benjamin B Kim Do Young DY Kennedy Elizabeth A EA Jo Jay-Hyun JH Shih Han-Yu HY Truong Amanda A Doebel Thomas T Sakamoto Keiko K Cui Chang-Yi CY Schlessinger David D Moro Kazuyo K Nakae Susumu S Horiuchi Keisuke K Zhu Jinfang J Leonard Warren J WJ Kong Heidi H HH Nagao Keisuke K
Cell 20190131 5
Immune cells and epithelium form sophisticated barrier systems in symbiotic relationships with microbiota. Evidence suggests that immune cells can sense microbes through intact barriers, but regulation of microbial commensalism remain largely unexplored. Here, we uncovered spatial compartmentalization of skin-resident innate lymphoid cells (ILCs) and modulation of sebaceous glands by a subset of RORγt<sup>+</sup> ILCs residing within hair follicles in close proximity to sebaceous glands. Their p ...[more]