Ontology highlight
ABSTRACT:
SUBMITTER: Watson OJ
PROVIDER: S-EPMC6533063 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Watson Oliver John OJ Verity Robert R Ghani Azra C AC Garske Tini T Cunningham Jane J Tshefu Antoinette A Mwandagalirwa Melchior K MK Meshnick Steven R SR Parr Jonathan B JB Slater Hannah C HC
eLife 20190502
Ten countries have reported <i>pfhrp2/pfhrp3</i> gene deletions since the first observation of <i>pfhrp2</i>-deleted parasites in 2012. In a previous study (Watson et al., 2017), we characterised the drivers selecting for <i>pfhrp2/3</i> deletions and mapped the regions in Africa with the greatest selection pressure. In February 2018, the World Health Organization issued guidance on investigating suspected false-negative rapid diagnostic tests (RDTs) due to <i>pfhrp2/3</i> deletions. However, no ...[more]