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A GEE-type approach to untangle structural and random zeros in predictors.


ABSTRACT: Count outcomes with excessive zeros are common in behavioral and social studies, and zero-inflated count models such as zero-inflated Poisson (ZIP) and zero-inflated Negative Binomial (ZINB) can be applied when such zero-inflated count data are used as response variable. However, when the zero-inflated count data are used as predictors, ignoring the difference of structural and random zeros can result in biased estimates. In this paper, a generalized estimating equation (GEE)-type mixture model is proposed to jointly model the response of interest and the zero-inflated count predictors. Simulation studies show that the proposed method performs well for practical settings and is more robust for model misspecification than the likelihood-based approach. A case study is also provided for illustration.

SUBMITTER: Ye P 

PROVIDER: S-EPMC6535372 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature

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A GEE-type approach to untangle structural and random zeros in predictors.

Ye Peng P   Tang Wan W   He Jiang J   He Hua H  

Statistical methods in medical research 20181126 12


Count outcomes with excessive zeros are common in behavioral and social studies, and zero-inflated count models such as zero-inflated Poisson (ZIP) and zero-inflated Negative Binomial (ZINB) can be applied when such zero-inflated count data are used as response variable. However, when the zero-inflated count data are used as predictors, ignoring the difference of structural and random zeros can result in biased estimates. In this paper, a generalized estimating equation (GEE)-type mixture model  ...[more]

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