Ontology highlight
ABSTRACT:
SUBMITTER: Lim J
PROVIDER: S-EPMC6536517 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Lim Jaejoon J Kim Min Jun MJ Park YoungJoon Y Ahn Ju Won JW Hwang So Jung SJ Moon Jong-Seok JS Cho Kyung Gi KG Kwack KyuBum K
Scientific reports 20190527 1
Inflammation in tumor microenvironments is implicated in the pathogenesis of tumor development. In particular, inflammasomes, which modulate innate immune functions, are linked to tumor growth and anticancer responses. However, the role of the NLRC4 inflammasome in gliomas remains unclear. Here, we investigated whether the upregulation of the NLRC4 inflammasome is associated with the clinical prognosis of gliomas. We analyzed the protein expression and localization of NLRC4 in glioma tissues fro ...[more]