Dataset Information

Effectiveness of integrative medicine program for dementia prevention on cognitive function and depression of elderly in a public health center.

ABSTRACT:

Background

This study investigated the effectiveness of an integrative medicine program (IMP) for dementia prevention on cognitive function, depression and quality of life (QOL) of elderly in a public health center.

Methods

This study employed a before-after study design to assess effectiveness of the IMP for dementia prevention for community dwelling elderly over 60 without diagnosis of dementia. Cognitive function was measured using the Mini Mental State Examination for Dementia screening (MMSE-DS), digit span test (DST) and trail making test (TMT). The Geriatric Depression Scale Short Form- Korean version (GDSSF-K) and EQ-5D were used to evaluate depression and health-related quality of life. The IMP composed of acupuncture, moxibustion, physical activities, meditation, laughter therapy and music therapy was held once a week over 8 weeks. A paired t-test was used to compare the pre and post-test results.

Results

After screening 93 people, a total of 48 were included in the analysis. Evaluation of the cognitive function revealed that TMT-A (p = 0.028) and TMT-B (p = 0.0013) were significantly reduced, but MMSE-DS (p = 0.309) and DST (DSF: p = 0.855, DSB: p = 0.176) were not statistically significant. Depression (p < 0.01) and preventive behavior for dementia (p < 0.0001) of the participants were improved after the IMP.

Conclusion

The IMP for dementia prevention may have beneficial effects on cognitive function and depression of elderly. However, a well-designed follow-up study is needed to confirm this conclusion.

SUBMITTER: Ahn HI

PROVIDER: S-EPMC6536738 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature

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Publications

Effectiveness of integrative medicine program for dementia prevention on cognitive function and depression of elderly in a public health center.

Ahn Hae In HI Hyun Min Kyung MK

Integrative medicine research 20190430 2

<h4>Background</h4>This study investigated the effectiveness of an integrative medicine program (IMP) for dementia prevention on cognitive function, depression and quality of life (QOL) of elderly in a public health center.<h4>Methods</h4>This study employed a before-after study design to assess effectiveness of the IMP for dementia prevention for community dwelling elderly over 60 without diagnosis of dementia. Cognitive function was measured using the Mini Mental State Examination for Dementia ...[more]

PMID: 31193590

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Project description:BackgroundThe Diabetes Prevention Program (DPP) was a randomized, controlled clinical trial. It demonstrated that among high-risk individuals with impaired glucose tolerance, diabetes incidence was reduced by 58 % with lifestyle intervention and 31 % with metformin compared to placebo. During the Diabetes Prevention Program Outcomes Study (DPPOS), all DPP participants were unmasked to their treatment assignments, the original lifestyle intervention group was offered additional lifestyle support, the metformin group continued metformin, and all three groups were offered a group-implemented lifestyle intervention. Over the 10 years of combined DPP/DPPOS follow-up, diabetes incidence was reduced by 34 % in the lifestyle group and 18 % in the metformin group compared to placebo. The purpose of this article is to review and synthesize analyses published by the DPP/DPPOS Research Group that have described the cost-effectiveness of diabetes prevention.MethodsWe describe the resource utilization and costs of the DPP and DPPOS interventions, the costs of non-intervention-related medical care, the impact of the interventions on diabetes progression and quality-of-life, and the cost-effectiveness of the interventions from health system and societal perspectives. Cost-effectiveness analyses were performed with a 3-year time horizon using DPP data, a lifetime time horizon that simulated 3-year DPP data, and a 10-year time horizon using combined DPP/DPPOS data.ResultsAlthough more expensive than the placebo intervention, the greater costs of the lifestyle and metformin interventions were offset by reductions in the costs of nonintervention-related medical care. Every year after randomization, quality-of-life was better for participants in the lifestyle intervention compared to those in the metformin or placebo intervention. In both the simulated lifetime analysis and the 10-year within trial economic analysis, lifestyle and metformin were extremely cost-effective (that is, improved outcomes at a low incremental cost) or even cost-saving (that is, improved outcomes and reduced total costs) compared to the placebo intervention.ConclusionsThe implementation of diabetes prevention programs in high-risk individuals will result in important health benefits and represents a good value for money.Trial registrationNCT00004992 (DPP) and NCT00038727 (DPPOS).

Dataset Information

Effectiveness of integrative medicine program for dementia prevention on cognitive function and depression of elderly in a public health center.

Background

Methods

Results

Conclusion

Publications

Effectiveness of integrative medicine program for dementia prevention on cognitive function and depression of elderly in a public health center.

Similar Datasets

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