Ontology highlight
ABSTRACT:
SUBMITTER: Mu Y
PROVIDER: S-EPMC6538264 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Nature chemistry 20190401 5
Nitriles are found in many bioactive compounds, and are among the most versatile functional groups in organic chemistry. Despite many notable recent advances, however, there are no approaches that may be used for the preparation of di- or tri-substituted alkenyl nitriles. Related approaches that are broad in scope and can deliver the desired products in high stereoisomeric purity are especially scarce. Here, we describe the development of several efficient catalytic cross-metathesis strategies, ...[more]