Unknown

Dataset Information

0

Comparison of prostate delineation on multimodality imaging for MR-guided radiotherapy.


ABSTRACT: OBJECTIVE::With increasing incorporation of MRI in radiotherapy, we investigate two MRI sequences for prostate delineation in radiographer-led image guidance. METHODS::Five therapeutic radiographers contoured the prostate individually on CT, T2 weighted (T2W) and T2* weighted (T2*W) imaging for 10 patients. Contours were analysed with Monaco ADMIRE (research v. 2.0) to assess interobserver variability and accuracy by comparison with a gold standard clinician contour. Observers recorded time taken for contouring and scored image quality and confidence in contouring. RESULTS::There is good agreement when comparing radiographer contours to the gold-standard for all three imaging types with Dice similarity co-efficient 0.91-0.94, Cohen's ? 0.85-0.91, Hausdorff distance 4.6-7.6?mm and mean distance between contours 0.9-1.2?mm. In addition, there is good concordance between radiographers across all imaging modalities. Both T2W and T2*W MRI show reduced interobserver variability and improved accuracy compared to CT, this was statistically significant for T2*W imaging compared to CT across all four comparison metrics. Comparing MRI sequences reveals significantly reduced interobserver variability and significantly improved accuracy on T2*W compared to T2W MRI for DSC and Cohen's ?. Both MRI sequences scored significantly higher compared to CT for image quality and confidence in contouring, particularly T2*W. This was also reflected in the shorter time for contouring, measuring 15.4, 9.6 and 9.8?min for CT, T2W and T2*W MRI respectively. Conclusion: Therapeutic radiographer prostate contours are more accurate, show less interobserver variability and are more confidently and quickly outlined on MRI compared to CT, particularly using T2*W MRI. Advances in knowledge: Our work is relevant for MRI sequence choice and development of the roles of the interprofessional team in the advancement of MRI-guided radiotherapy.

SUBMITTER: Pathmanathan AU 

PROVIDER: S-EPMC6540870 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature

altmetric image

Publications

Comparison of prostate delineation on multimodality imaging for MR-guided radiotherapy.

Pathmanathan Angela U AU   McNair Helen A HA   Schmidt Maria A MA   Brand Douglas H DH   Delacroix Louise L   Eccles Cynthia L CL   Gordon Alexandra A   Herbert Trina T   van As Nicholas J NJ   Huddart Robert A RA   Tree Alison C AC  

The British journal of radiology 20190124 1095


<h4>Objective:</h4>With increasing incorporation of MRI in radiotherapy, we investigate two MRI sequences for prostate delineation in radiographer-led image guidance.<h4>Methods:</h4>Five therapeutic radiographers contoured the prostate individually on CT, T<sub>2</sub> weighted (T<sub>2</sub>W) and T<sub>2</sub>* weighted (T<sub>2</sub>*W) imaging for 10 patients. Contours were analysed with Monaco ADMIRE (research v. 2.0) to assess interobserver variability and accuracy by comparison with a go  ...[more]

Similar Datasets

| S-EPMC7757637 | biostudies-literature
| S-EPMC5976174 | biostudies-literature
| S-EPMC6700415 | biostudies-literature
| S-EPMC6785785 | biostudies-literature
| S-EPMC7947660 | biostudies-literature
| S-EPMC7674276 | biostudies-literature
| S-EPMC4572575 | biostudies-literature
| S-EPMC8019940 | biostudies-literature
| S-EPMC7399349 | biostudies-literature
| S-EPMC10902126 | biostudies-literature