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State-of-the-art radionuclide imaging in cardiac transthyretin amyloidosis.

ABSTRACT: Cardiac amyloidosis, once considered untreatable, is now gaining well-deserved attention due to advances in imaging and the recent approval of targeted breakthrough therapies. In this paper, we discuss the role of radionuclide imaging in the evaluation and management of patients with the most common form of amyloidosis-cardiac transthyretin amyloidosis (ATTR). We provide a comprehensive summary of the literature interspersed with our institutional experience as appropriate, to deliver our perspective.

SUBMITTER: Singh V 

PROVIDER: S-EPMC6541031 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature

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State-of-the-art radionuclide imaging in cardiac transthyretin amyloidosis.

Singh Vasvi V   Falk Rodney R   Di Carli Marcelo F MF   Kijewski Marie M   Rapezzi Claudio C   Dorbala Sharmila S  

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 20181219 1

Cardiac amyloidosis, once considered untreatable, is now gaining well-deserved attention due to advances in imaging and the recent approval of targeted breakthrough therapies. In this paper, we discuss the role of radionuclide imaging in the evaluation and management of patients with the most common form of amyloidosis-cardiac transthyretin amyloidosis (ATTR). We provide a comprehensive summary of the literature interspersed with our institutional experience as appropriate, to deliver our perspe  ...[more]

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