Ontology highlight
ABSTRACT:
SUBMITTER: Mikulska-Ruminska K
PROVIDER: S-EPMC6541894 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Mikulska-Ruminska Karolina K Shrivastava Indira I Krieger James J Zhang She S Li Hongchun H Bayır Hülya H Wenzel Sally E SE VanDemark Andrew P AP Kagan Valerian E VE Bahar Ivet I
Journal of chemical information and modeling 20190228 5
Accurate modeling of structural dynamics of proteins and their differentiation across different species can help us understand generic mechanisms of function shared by family members and the molecular basis of the specificity of individual members. We focused here on the family of lipoxygenases, enzymes that catalyze lipid oxidation, the mammalian and bacterial structures of which have been elucidated. We present a systematic method of approach for characterizing the sequence, structure, dynamic ...[more]